Simulations - FRAGM

Virtual Lab Engine

Precision simulation tools for genomic research.

Advanced computational modules for DNA fragmentation, modeling enzymatic and mechanical processes with high-fidelity data outputs.

ENG-01Core Engine

Hydrodynamic Shearing

Simulate mechanical DNA fragmentation using controlled fluid dynamics. Optimize shear rates for specific fragment size distributions.

Adjustable flow velocity and pressure parameters

Real-time visualization of shearing forces

Predictive yield analysis for downstream sequencing

Automated protocol optimization for library prep

Shear Rate Control0.5-50 kb Range

Launch Shear Engine

ENG-02

Acoustic Ultrasonication

Model cavitation-based fragmentation. Precisely calibrate duty cycles and pulse durations to achieve target fragment lengths.

Dynamic duty cycle and frequency modulation

Thermal degradation risk monitoring

Automated cavitation bubble density tracking

Protocol presets for various DNA inputs

Pulse Calibration99.8% Accuracy

View Sonicator Specs

ENG-03

Enzymatic Digestion

Simulate restriction endonuclease cleavage. Model enzyme kinetics, incubation times, and buffer conditions for specific cuts.

Customizable enzyme concentration and activity

Automated cleavage site prediction

Buffer condition and pH sensitivity modeling

Instant fragment size distribution reports

Kinetics Modeling20+ Enzyme Profiles

See Enzyme Suite

ENG-04

End-Repair Modeling

Simulate end-repair and A-tailing processes. Ensure optimal fragment ends for adapter ligation and library efficiency.

Real-time ligation efficiency simulation

Automated adapter-dimer formation alerts

Fragment end-polishing kinetics tracking

Batch-wise yield optimization tools

Ligation Efficiency95% Yield Target

Explore Repair Tools

ENG-05

Fragment Analytics

Comprehensive data visualization for fragment size distribution, yield analysis, and quality control metrics.

Automated peak detection and sizing

Comparative analysis of multiple runs

Exportable distribution plots and CSV data

Quality score generation for library prep

Auto-Peak DetectionRFU Data Output

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Need custom protocols or data integration?

Our team supports custom protocol development and seamless integration with your existing lab data pipelines.

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Analytical Suite

Advanced Data Visualization

Master your DNA fragmentation experiments with high-fidelity analytical tools and real-time telemetry.

Precision

Peak Size Calculator

Automated detection of fragment distribution peaks with high-precision base-pair length estimation.

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PDI Metrics

Polydispersity Index

Quantify fragment size distribution uniformity to ensure optimal library preparation quality.

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Visual Match

Gel Overlay View

Simulated TapeStation electropherogram overlays for direct comparison against experimental data.

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Raw Data

Data Export Suite

Download raw simulation telemetry in CSV or FASTA formats for downstream bioinformatics analysis.

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Validated

Protocol Mapping

Sync simulation parameters with standard lab protocols to validate experimental yield targets.

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Reference

Benchmarking Tools

Compare fragment size distribution across multiple virtual runs with global reference standards.

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Ready to analyze your results?

Access the full suite of analytical tools for your research project today.

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Lab Systems Online|

Nodes: 842 Active

Sim Latency: 0.4ms

Virtual DNA fragmentation laboratory for research and education. Simulate complex shearing protocols with zero waste.

v4.1.0-corebio-engine

High-fidelity biophysical simulation.

Platform

Experiments

Resources